Main Article Content
Systematic reviews and meta-analyses are vital methodologies in medical research that consolidate and assess evidence pertaining to specific research questions. Systematic reviews adopt a meticulous approach to pinpoint, evaluate, and integrate all pertinent studies on a given topic. Conversely, meta-analyses employ statistical methods to amalgamate results from several studies, yielding a combined estimate of intervention effects or identifying patterns across research.
Both methodologies hold paramount significance in medicine, aiding researchers, clinicians, and policymakers in comprehending the comprehensive evidence on a subject. They underpin evidence-based decision-making, reconcile conflicting results, augment statistical power, spotlight research voids, steer policy and clinical guidelines, optimize resource use, and bolster patient comprehension.
This paper delves into the paramountcy of systematic reviews and meta-analysis in the realm of medicine. It underscores their myriad advantages and their pivotal role in enriching medical knowledge. Contemporary, real-world examples are furnished to elucidate these points. In essence, this paper offers an insightful exposition on the cruciality of systematic reviews and meta-analysis in medicine, underscoring their role in anchoring medical practice in top-tier evidence and ensuring the zenith of patient care.
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Ioannidis JP. The Mass Production of Redundant, Misleading, and Conflicted Systematic Reviews and Meta-analyses. Milbank Q. 2016;94(3):485-514.
Smela B, Toumi M, Swierk K, Gawlik K, Clay E, Boyer L. Systematic literature reviews over the years. J Mark Access Health Policy. 2023;11(1):2244305.
Uman LS. Systematic reviews and meta-analyses. J Can Acad Child Adolesc Psychiatry. 2011;20(1):57-9.
Auladell-Rispau A, Bendersky J, Santafe A, Buchanan C, Rigau Comas D, Verdugo F, et al. Methodological approaches for developing and reporting living evidence synthesis: a study protocol. Open Res Eur. 2021;1:113.
Taghizadeh S, Hashemi MG, Zarnag RK, Fayyazishishavan E, Gholami M, Farhangi MA, Gojani LJ. Barriers and facilitators of childhood obesity prevention policies: A systematic review and meta-synthesis. Front Pediatr. 2022;10:1054133.
Bello A, Wiebe N, Garg A, Tonelli M. Evidence-based decision-making 2: Systematic reviews and meta-analysis. Methods Mol Biol. 2015;1281:397-416.
Vavken P, Dorotka R. A systematic review of conflicting meta-analyses in orthopaedic surgery. Clin Orthop Relat Res. 2009;467(10):2723-35.
Cohn LD, Becker BJ. How meta-analysis increases statistical power. Psychol Methods. 2003;8(3):243-53.
Ghasemirad M, Ketabi L, Fayyazishishavan E, Hojati A, Maleki ZH, Gerami MH, et al. The association between screen use and central obesity among children and adolescents: a systematic review and meta-analysis. J Health Popul Nutr. 2023;42(1):51.
Dahm P, Yeung LL, Gallucci M, Simone G, Schunemann HJ. How to use a clinical practice guideline. J Urol. 2009;181(2):472-9.
Kang H. Statistical considerations in meta-analysis. Hanyang Medical Reviews. 2015;35(1):23-32.
Tseng TY, Dahm P, Poolman RW, Preminger GM, Canales BJ, Montori VM. How to use a systematic literature review and meta-analysis. J Urol. 2008;180(4):1249-56.
Rahmani E, Fayyazishishavan E, Afzalian A, Varshochi S, Amani-Beni R, Ahadiat SA, et al. Point-Of-Care Ultrasonography for Identification of Skin and Soft Tissue Abscess in Adult and Pediatric Patients; a Systematic Review and Meta-Analysis. Arch Acad Emerg Med. 2023;11(1):e49.
Rahmani E, Amani-Beni R, Hekmatnia Y, Fakhre Yaseri A, Ahadiat SA, Talebi Boroujeni P, et al. Diagnostic Accuracy of Ultrasonography for Detection of Intussusception in Children; a Systematic Review and Meta-Analysis. Arch Acad Emerg Med. 2023;11(1):e24.
Pai M, McCulloch M, Gorman JD, Pai N, Enanoria W, Kennedy G, et al. Systematic reviews and meta-analyses: an illustrated, step-by-step guide. Natl Med J India. 2004;17(2):86-95.
Delaney A, Bagshaw SM, Ferland A, Laupland K, Manns B, Doig C. The quality of reports of critical care meta-analyses in the Cochrane Database of Systematic Reviews: an independent appraisal. Crit Care Med. 2007;35(2):589-94.
Moher D, Cook DJ, Eastwood S, Olkin I, Rennie D, Stroup DF. Improving the quality of reports of meta-analyses of randomised controlled trials: the QUOROM statement. The Lancet. 1999;354(9193):1896-900.
Mokhtari-Ardekani A, Fayyazishishavan, E., Akhavanfar, R. Abbasalizad-Farhangi, M. Circulating Advanced Oxidation Protein Products (AOPPs) increases the risk of metabolic syndrome among adults: A systematic review and meta-analysis. International Journal of Diabetes in Developing Countries. 2023.
Kazemi SM, Khorram R, Fayyazishishavan E, Amani-Beni R, Haririan Y, Hosseini Khameneh SM, et al. Diagnostic Accuracy of Ottawa Knee Rule for Diagnosis of Fracture in Patients with Knee Trauma; a Systematic Review and Meta-analysis. Arch Acad Emerg Med. 2023;11(1):e30.
Ahn E, Kang H. Introduction to systematic review and meta-analysis. Korean J Anesthesiol. 2018;71(2):103-12.