Main Article Content
This paper describes a simple method for segmenting the hippocampus automatically from high-resolution 9.4 Tesla MRI of postmortem samples. Large datasets of high-resolution structural MR images are collected to quantitatively analyze the relationships between brain anatomy, disease progression, treatment regimens, and genetic influences upon brain structure.This method segments the hippocampus without any human intervention for few slices present in the anterior and the posterior position in the total volume. Experimental results using this method show a good agreement with the manuals segmented gold standard.
Keywords: Hippocampus; amygdale; post-mortem; Alzheimerâ€™s disease; neuropathology; morphometry; cornu ammonis; dentate gyrus
Submission of a manuscript implies: that the work described has not been published before, that it is not under consideration for publication elsewhere; that if and when the manuscript is accepted for publication, the authors agree to automatic transfer of the copyright to the publisher.
Authors who publish with this journal agree to the following terms:
- Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgment of the work's authorship and initial publication in this journal.
- Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgment of its initial publication in this journal.
- Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work
- The journal allows the author(s) to retain publishing rights without restrictions.
- The journal allows the author(s) to hold the copyright without restrictions.